I’ve never taken a sleeping pill, and I don’t recommend doing so as I’m not a doctor. But if your doctor does prescribe you a sleeping pill—for a long flight, for example—you don’t want to take it for the first time on a plane. You don’t know how your body will react to the new medication, and stuck in a tube in the sky is not a great setting for finding out.
As for when to take a known sleeping pill, you should again consult your doctor first—and you might want to wait until after takeoff, based on the story of this WestJet passenger.
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